The Interprofessional Quality Improvement Projects are an opportunity for students to engage in health system problems and devise novel solutions to the challenges facing the healthcare systems. The students from medicine, nursing and pharmacy in collaboration with faculty from these schools and staff from the VCU Health System’s Performance Improvement Group, select a quality improvement problem from a menu of health system priorities. Then, the students study the problem and develop an approach to test in the clinical environment. Through the experience, students learn about the other profession and how to lead interprofessional quality improvement in our modern healthcare environment. Outcomes from the experience have been featured in national forums.